Anti Thyroid Medicines

Product Details:

Oral levothyroxine is primarily indicated for treating primary, secondary, and tertiary hypothyroidism. Primary hypothyroidism is when the problem occurs in the thyroid gland. Secondary hypothyroidism is when the problem is in the pituitary gland, and there is a decrease in the production of thyroid-stimulating hormone (TSH). Tertiary hypothyroidism is sporadic. Additionally, levothyroxine has FDA approval for pituitary thyrotropin suppression as an adjunct to surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. This activity covers important information about prescribing levothyroxine, including mechanism of action, pharmacology, adverse event profiles, eligible patient populations, and monitoring, and highlights the interprofessional team's role in managing various forms of hypothyroidism with levothyroxine.

Additional Information:

• Production Capacity: 25000 BOTTLES PER MONTH
• Delivery Time: 2-5 DAYS
• Packaging Details: ALL MEDICINES ARE WELL PACKED IN BROWN CARD BOX WITH THARMACOLE AND PLASTIC TO MAKE DECENT PACKING AND PREVENT FROM ANY TYPE OF PRODUCT DAMAGE .

Product Details:

Thyroxine Sodium Tablet 150 mcg is a synthetic thyroid hormone replacement used to treat conditions where the thyroid gland does not produce enough hormones.

Composition & Class

• Active ingredient: Levothyroxine sodium (synthetic form of the natural thyroid hormone T4 – thyroxine).

• Strength: 150 mcg (micrograms) per tablet.

• Class: Thyroid hormone replacement.

Mechanism of Action

• Levothyroxine is a synthetic version of thyroxine (T4), which is normally secreted by the thyroid gland.

• In the body, T4 is converted into the active form triiodothyronine (T3).

• T3 enters cells and binds to thyroid receptors in the nucleus → regulates gene expression → controls metabolism, growth, and development.

• Restores normal thyroid hormone levels when the body’s natural production is insufficient.

Indications (Uses)

1. Hypothyroidism (underactive thyroid):

   • Primary hypothyroidism (Hashimoto’s thyroiditis, thyroid surgery, radioactive iodine treatment, etc.)

   • Secondary or tertiary hypothyroidism (pituitary or hypothalamic causes)

2. Goiter (enlarged thyroid gland, to reduce size)

3. Thyroid cancer (to suppress TSH and prevent cancer recurrence)

4. Myxedema coma (life-threatening severe hypothyroidism, usually IV form)

5. Used in TSH suppression test in thyroid diagnostics.

Dosage & Administration

• Usual adult replacement dose: 50–200 mcg daily (varies by age, weight, and severity).

• This specific tablet is 150 mcg, often used in patients who require a higher dose.

• Taken once daily in the morning on an empty stomach, at least 30–60 minutes before breakfast, with water only.

• Avoid taking with calcium, iron, soy, or antacids within 4 hours, as they reduce absorption.

• Dose adjustments are based on TSH (thyroid-stimulating hormone) blood tests every 6–8 weeks initially.

Side Effects (usually occur if the dose is too high → hyperthyroid symptoms)

• Palpitations, rapid heartbeat (tachycardia)

• Tremors, anxiety, irritability

• Insomnia, headache

• Weight loss despite increased appetite

• Heat intolerance, sweating

• Diarrhea

• Long-term excess → osteoporosis, atrial fibrillation, heart problems

Precautions

• Start with low dose in elderly or cardiac patients to avoid strain on the heart.

• Regular monitoring of TSH and T4 levels is necessary.

• Should not be used for weight loss in people with normal thyroid function (dangerous misuse).

• Adjust dose in pregnancy (requirements often increase).

• Interaction with many drugs (antidiabetics, anticoagulants like warfarin, antiepileptics, calcium/iron supplements, etc.).

Additional Information:

• Production Capacity: 25000 Bottles per month
• Delivery Time: 2-5 Days
• Packaging Details: ALL MEDICINES ARE WELL PACKED IN BROWN CARD BOX WITH THARMACOLE AND PLASTIC TO MAKE DECENT PACKING AND PREVENT FROM ANY TYPE OF PRODUCT DAMAGE .

Product Details:

T3 Tab Liothyronine 25 mg contains liothyronine sodium, which is a synthetic form of the thyroid hormone triiodothyronine (T3). Thyroid hormones, including T3, play a crucial role in regulating various metabolic processes in the body, such as metabolism, growth, and energy expenditure. Liothyronine is used primarily to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones. Liothyronine is typically prescribed in cases where levothyroxine (a synthetic form of thyroxine or T4) alone is not sufficient in managing hypothyroidism. It may be prescribed for individuals who do not adequately convert T4 to T3 or those who require more immediate correction of T3 levels. As with any medication, it's essential to take liothyronine exactly as prescribed by a healthcare professional and to follow their instructions regarding dosage and duration of treatment. It's also important to attend regular follow-up appointments to monitor thyroid hormone levels and adjust the dosage if necessary.

Additional Information:

• Production Capacity: 25000 Strips per month
• Delivery Time: 2-5 Days
• Packaging Details: ALL MEDICINES ARE WELL PACKED IN BROWN CARD BOX WITH THARMACOLE AND PLASTIC TO MAKE DECENT PACKING AND PREVENT FROM ANY TYPE OF PRODUCT DAMAGE .

Product Details:

• Liothyronine is a synthetic form of triiodothyronine (T3), one of the two main thyroid hormones (the other is thyroxine/T4).

• Available as 25 mg tablets, though in practice it’s usually prescribed in micrograms (µg) (commonly 5 µg, 25 µg, 50 µg) because thyroid hormones are very potent.

• Used when the body does not produce enough thyroid hormone (hypothyroidism) or when extra T3 is needed.

🔹 Mechanism of Action

• T3 (Liothyronine) enters cells and binds to thyroid hormone receptors in the nucleus.

• This regulates gene transcription and protein synthesis → increases the metabolic rate of nearly every tissue.

• Key actions include:

  • Stimulating oxygen consumption.

  • Regulating growth and development.

  • Enhancing carbohydrate, protein, and fat metabolism.

  • Supporting heart function, body temperature, and nervous system activity.

🔹 Medical Uses

1. Hypothyroidism – if the thyroid gland does not produce enough hormones.

2. Myxedema coma – a severe, life-threatening hypothyroidism (usually given IV in hospitals).

3. Goiter treatment – to reduce thyroid enlargement.

4. Thyroid cancer – as part of suppression therapy after surgery.

5. Diagnostic use – T3 suppression test (rarely used today).

6. Sometimes used in combination with levothyroxine (T4) in patients who do not feel well on T4 alone.

🔹 Dosage & Administration

• Adult starting dose: usually 25 mcg daily (not mg – mcg = microgram).

• Adjusted every 1–2 weeks by 12.5–25 mcg depending on response.

• Typical maintenance dose: 25–75 mcg daily.

• Taken orally, usually in the morning, on an empty stomach for best absorption.

⚠️ If your medicine says 25 mg, it may be a labeling error — therapeutic doses are in micrograms (µg), not milligrams, since 25 mg would be massively toxic.

🔹 Side Effects

Too much liothyronine = symptoms of hyperthyroidism (overactive thyroid):

• Nervousness, anxiety, irritability.

• Sweating, heat intolerance.

• Palpitations, rapid heartbeat (tachycardia).

• Weight loss despite good appetite.

• Tremors, insomnia.

• Diarrhea.

Serious risks:

• Angina, arrhythmias, heart failure (especially in older patients).

• Osteoporosis (long-term high doses).

🔹 Contraindications & Precautions

• Contraindicated in:

  • Untreated adrenal insufficiency.

  • Acute myocardial infarction.

  • Uncorrected thyrotoxicosis (already high thyroid hormone).

• Use with caution in:

  • Heart disease, arrhythmias, hypertension.

  • Elderly patients.

  • Diabetics (may affect insulin/glucose control).

🔹 Drug Interactions

• Anticoagulants (warfarin): ↑ bleeding risk.

• Diabetes medications: may require dose adjustment.

• Sympathomimetics (like adrenaline): ↑ heart side effects.

• Antacids, iron, calcium, soy: reduce absorption (take liothyronine 4 hours apart).

Additional Information:

• Production Capacity: 25000 Strips per month
• Delivery Time: 2-5 Days
• Packaging Details: ALL MEDICINES ARE WELL PACKED IN BROWN CARD BOX WITH THARMACOLE AND PLASTIC TO MAKE DECENT PACKING AND PREVENT FROM ANY TYPE OF PRODUCT DAMAGE .

Product Details:

Levothyroxine 100 mcg Tablet

Category: Thyroid hormone replacement (synthetic form of thyroxine – T4).

Main Uses

1. Hypothyroidism (Underactive thyroid)

   • Primary use.

   • Replaces deficient thyroid hormone.

   • Improves symptoms like fatigue, weight gain, constipation, hair fall, dry skin, depression, and slow heart rate.

2. Goiter (Enlarged thyroid gland)

   • Used to shrink the gland or prevent further enlargement.

3. Thyroid Cancer

   • After surgical removal of thyroid (thyroidectomy), levothyroxine is used to suppress TSH (Thyroid Stimulating Hormone), since TSH can stimulate cancer recurrence.

4. Post-Thyroid Surgery / Radioactive Iodine Therapy

   • To replace missing thyroid hormones if the gland is partially/fully destroyed or removed.

5. Congenital Hypothyroidism (in infants/children)

   • Ensures proper growth and brain development.

How It Works

• Levothyroxine is converted in the body to the active form T3 (triiodothyronine).

• Regulates metabolism, energy production, body temperature, and growth.

Dosage

• Taken once daily in the morning, on an empty stomach, at least 30–60 minutes before breakfast.

• 100 mcg is a common adult maintenance dose, but the dose is individualized based on TSH blood test results, age, weight, and health conditions.

Side Effects (usually if dose is too high)

• Palpitations, fast heartbeat

• Anxiety, irritability

• Insomnia

• Weight loss, sweating, tremors

• Long-term excess dose → risk of osteoporosis, atrial fibrillation, heart strain

Precautions

• Regular TSH monitoring is needed.

• Dose adjustment required in pregnancy, elderly, or those with heart disease.

• Should not be taken with calcium, iron, antacids, or soy products at the same time (reduces absorption).

 

Additional Information:

• Production Capacity: 25000 Bottles per month
• Delivery Time: 2-5 Days
• Packaging Details: ALL MEDICINES ARE WELL PACKED IN BROWN CARD BOX WITH THARMACOLE AND PLASTIC TO MAKE DECENT PACKING AND PREVENT FROM ANY TYPE OF PRODUCT DAMAGE .