Vaginal Gel

Product Details:

Conjugated Estrogens (0.625 mg) Cream

Category: Hormone replacement therapy (HRT)
Form: Vaginal cream
Active ingredient: Conjugated estrogens (mixture of estrogen hormones)

1. Menopausal Symptoms (Local/Vaginal)

   • Treats atrophic vaginitis (thinning, drying, and inflammation of vaginal walls due to estrogen deficiency).

   • Relieves vaginal dryness, burning, itching, and pain during intercourse (dyspareunia).

   • Improves vaginal elasticity and lubrication.

2. Urinary Symptoms (Postmenopausal Urogenital Syndrome)

   • Helps reduce urinary urgency, frequency, recurrent urinary tract infections (UTIs), and mild stress incontinence related to estrogen loss.

3. Other Indications (as prescribed)

   • Sometimes used in female hypogonadism or ovarian failure, when estrogen replacement is required.

   • May be prescribed after surgical removal of ovaries (oophorectomy) to relieve local vaginal symptoms.

• Provides local estrogen supplementation directly to vaginal tissues.

• Restores epithelial thickness, elasticity, and blood flow in vaginal and urinary tissues.

• Minimizes systemic absorption compared to oral estrogen, so mainly acts locally.

• Usually applied once daily at bedtime for 1–2 weeks, then reduced to a maintenance dose (e.g., 2–3 times per week) as advised by doctor.

• Dose and frequency depend on severity of symptoms.

Local:

• Vaginal irritation, itching, or discharge

• Spotting or breakthrough bleeding (rare)

Systemic (less common, but possible if absorbed):

• Breast tenderness or enlargement

• Headache, nausea

• Fluid retention, leg cramps

Long-term risks (if used in higher/systemic doses):

• Increased risk of endometrial hyperplasia (if uterus present, often combined with progesterone to reduce risk)

• Small increased risk of breast cancer, stroke, or blood clots with systemic absorption

• Not for use in women with history of breast cancer, estrogen-dependent tumors, blood clots, liver disease, or unexplained vaginal bleeding.

• Should be used at lowest effective dose for shortest duration.

• Regular medical checkups (pelvic exam, breast exam, Pap smear) are recommended.

Additional Information:

• Production Capacity: 25000 Tubes per month
• Delivery Time: 2-5 Days
• Packaging Details: ALL MEDICINES ARE WELL PACKED IN BROWN CARD BOX WITH THARMACOLE AND PLASTIC TO MAKE DECENT PACKING AND PREVENT FROM ANY TYPE OF PRODUCT DAMAGE .

Product Details:

• Brand Name: Susten Gel 8%

• Active Ingredient: Progesterone 8% w/w (natural micronized progesterone)

• Formulation: Vaginal gel (8% means 80 mg progesterone per gram of gel)

• Category: Hormone replacement / Progestogen therapy

• Manufacturer: Commonly marketed by Sun Pharma (India) and others.

Progesterone is a natural female hormone.

• After ovulation, progesterone prepares the endometrium (uterine lining) for implantation of a fertilized egg.

• It supports early pregnancy by maintaining the uterine lining and reducing uterine contractions.

• In assisted reproductive techniques (ART – IVF, IUI, embryo transfer), external progesterone helps when the body does not produce enough.

• Vaginal delivery of progesterone gives direct effect on uterus with fewer systemic side effects compared to oral tablets.

Susten Gel 8% is prescribed for:

1. Infertility treatment & IVF support – to prepare endometrium for embryo implantation.

2. Luteal phase support in women with insufficient natural progesterone.

3. Threatened miscarriage (when progesterone deficiency suspected).

4. Habitual/recurrent miscarriage due to luteal phase defects.

5. Hormone replacement therapy (HRT) in postmenopausal women (along with estrogen, to protect uterus).

• Applied vaginally, usually with an applicator.

• Standard dose: One applicatorful (approx. 1 g = 90 mg progesterone) once or twice daily (as prescribed).

• Timing depends on fertility treatment protocol or doctor’s instructions.

• Best applied while lying down, usually at night.

Local (most common):

• Vaginal irritation, itching, discharge

• Burning sensation or discomfort

Systemic (less common, mild):

• Breast tenderness

• Headache, mood swings, drowsiness

• Abdominal bloating, nausea

Serious (rare):

• Allergic reaction

• Vaginal bleeding (should be reported immediately)

• Blood clotting issues (very rare, mostly in women with risk factors)

• Use only under medical supervision, especially in fertility treatments.

• Not for use in women with:

  • Unexplained vaginal bleeding

  • History of breast or genital cancers

  • Severe liver disease

  • Active or history of blood clots (DVT, pulmonary embolism)

• Not to be used orally – only vaginal application.

• Safe in pregnancy when prescribed, but not recommended during breastfeeding without doctor’s advice.

Additional Information:

• Production Capacity: 25000 pouch per month
• Delivery Time: 2-5 Days
• Packaging Details: ALL MEDICINES ARE WELL PACKED IN BROWN CARD BOX WITH THARMACOLE AND PLASTIC TO MAKE DECENT PACKING AND PREVENT FROM ANY TYPE OF PRODUCT DAMAGE .